COMMUNICATIONS
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3011-3013
A Novel Acetylated Analogue of Dynorphin A-(1-11) Amide as a -Opioid Receptor Antagonist
Qiang Wan,
Thomas F. Murray, and
Jane V. Aldrich
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3014-3017
Synthesis and Enantiomeric Separation of 2-Phthalimidino-glutaric Acid Analogues: Potent Inhibitors of Tumor Metastasis
Jamshed H. Shah,
Glenn M. Swartz,
Adonia E. Papathanassiu,
Anthony M. Treston,
William E. Fogler,
John W. Madsen, and
Shawn J. Green
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3018-3022
Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood Stabilities
David Bom,
Dennis P. Curran,
Ashok J. Chavan,
Stefan Kruszewski,
Stephen G. Zimmer,
Kimberly A. Fraley, and
Thomas G. Burke
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3023-3025
Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors
Laval Chan,
Haolun Jin,
Tomislav Stefanac,
Jean-François Lavallée,
Guy Falardeau,
Wei Wang,
Jean Bédard,
Suzanne May, and
Leonard Yuen
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3026-3032
Discovery and Synthesis of (S)-3-[2-(3,4-Dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic Acid (LU 302872), a Novel Orally Active Mixed ETA/ETB Receptor Antagonist
Willi Amberg,
Stefan Hergenröder,
Heinz Hillen,
Rolf Jansen,
Georg Kettschau,
Andreas Kling,
Dagmar Klinge,
Manfred Raschack,
Hartmut Riechers, and
Liliane Unger
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3033-3040
N-Methylated Cyclic RGD Peptides as Highly Active and Selective V3 Integrin Antagonists
Michael A. Dechantsreiter,
Eckart Planker,
Barbara Mathä,
Elisabeth Lohof,
Günter Hölzemann,
Alfred Jonczyk,
Simon L. Goodman, and
Horst Kessler
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3041-3054
Synthesis, Evaluation, and Comparative Molecular Field Analysis of 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as Ligands for Histamine H1 Receptors
Ehren C. Bucholtz,
Randal L. Brown,
Alexander Tropsha,
Raymond G. Booth, and
Steven D. Wyrick
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3055-3065
Chiral Resolution and Stereospecificity of 6-Phenyl-4-phenylethynyl- 1,4-dihydropyridines as Selective A3 Adenosine Receptor Antagonists
Ji-long Jiang,
An-Hu Li,
Soo-Yeon Jang,
Louis Chang,
Neli Melman,
Stefano Moro,
Xiao-duo Ji,
Emil B. Lobkovsky,
Jon C. Clardy, and
Kenneth A. Jacobson
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3066-3074
Molecular Recognition in Nicotinic Acetylcholine Receptors: The Importance of PI-Cation Interactions
Jeffrey D. Schmitt,
Christopher G. V. Sharples, and
W. S. Caldwell
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3075-3086
Ochratoxin Binding to Phenylalanyl-tRNA Synthetase: Computational Approach to the Mechanism of Ochratoxicosis and Its Antagonism
Daniel R. McMasters and
Angelo Vedani
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3087-3093
Lipophilic 4-Isoxazolyl-1,4-dihydropyridines: Synthesis and Structure-Activity Relationships
Nicholas R. Natale,
Mark E. Rogers,
Richard Staples,
David J. Triggle, and
Aleta Rutledge
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3094-3100
Novel Prodrug Approach for Tertiary Amines: Synthesis and Preliminary Evaluation of N-Phosphonooxymethyl Prodrugs
Jeffrey P. Krise,
Jan Zygmunt,
Gunda I. Georg, and
Valentino J. Stella
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3101-3108
Synthesis and Characterization of Fluorescent Ligands for the Norepinephrine Transporter: Potential Neuroblastoma Imaging Agents
Dirk Hadrich,
Frank Berthold,
Eberhard Steckhan, and
Heinz Bönisch
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3109-3115
Potent Bivalent Thrombin Inhibitors: Replacement of the Scissile Peptide Bond at P1-P1' with Arginyl Ketomethylene Isosteres
Torsten Steinmetzer,
Bing Yan Zhu, and
Yasuo Konishi
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3116-3125
Novel Hypotensive Agents from Verbesina caracasana. 6. Synthesis and Pharmacology of Caracasandiamide
Marco Carmignani,
Anna R. Volpe,
Franco Delle Monache,
Bruno Botta,
Romulo Espinal,
Stella C. De Bonnevaux,
Carlo De Luca,
Maurizio Botta,
Federico Corelli,
Andrea Tafi,
Giuseppe Ripanti, and
Giuliano Delle Monache
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3126-3133
Carboxylic Acid Analogues of Tamoxifen: (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine. Estrogen Receptor Affinity and Estrogen Antagonist Effects in MCF-7 Cells
Kelly S. Kraft,
Peter C. Ruenitz, and
Michael G. Bartlett
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3134-3146
Novel Calcium Antagonists with Both Calcium Overload Inhibition and Antioxidant Activity. 2. Structure-Activity Relationships of Thiazolidinone Derivatives
Tatsuya Kato,
Tomokazu Ozaki,
Kazuhiko Tamura,
Yoshiyuki Suzuki,
Michitaka Akima, and
Nobuhiro Ohi
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3147-3153
N-Nitroarginine-Containing Dipeptide Amides. Potent and Highly Selective Inhibitors of Neuronal Nitric Oxide Synthase
Hui Huang,
Pavel Martasek,
Linda J. Roman,
Bettie Sue Siler Masters, and
Richard B. Silverman
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3154-3162
Development of Predictive Retention-Activity Relationship Models of Tricyclic Antidepressants by Micellar Liquid Chromatography
C. Quiñones-Torrelo,
S. Sagrado,
R. M. Villanueva-Camañas, and
M. J. Medina-Hernández
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3163-3166
New Type of Febrifugine Analogues, Bearing a Quinolizidine Moiety, Show Potent Antimalarial Activity against Plasmodium Malaria Parasite
Yoshiaki Takaya,
Hidehisa Tasaka,
Tomoyuki Chiba,
Koji Uwai,
Masa-aki Tanitsu,
Hye-Sook Kim,
Yusuke Wataya,
Masatomo Miura,
Mitsuhiro Takeshita, and
Yoshiteru Oshima
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3167-3174
Cytotoxicity of 2,2':6',2' '-Terpyridineplatinum(II) Complexes against Human Ovarian Carcinoma
Gordon Lowe,
Anne Sophie Droz,
Tirayut Vilaivan,
George W. Weaver,
Jenny J. Park,
Jonathan M. Pratt,
Lindsay Tweedale, and
Lloyd R. Kelland
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3175-3182
Constrained Corticotropin Releasing Factor Antagonists (Astressin Analogues) with Long Duration of Action in the Rat
Jean E. Rivier,
Dean A. Kirby,
Sabine L. Lahrichi,
Anne Corrigan,
Wylie W. Vale, and
Catherine L. Rivier
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3183-3187
Robust QSAR Models Using Bayesian Regularized Neural Networks
Frank R. Burden
, David A. Winkler
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3188-3192
Synthesis and Biological Activity of the Superestrogen (E)-17-Oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: X-ray Crystal Structure of (E)-17-Oximino-3-hydroxy-1,3,5(10)-estratriene
Hatem A. M. Hejaz,
Atul Purohit,
Mary F. Mahon,
Michael J. Reed, and
Barry V. L. Potter
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